Charles Czuprynski
Department of Pathobiological Sciences
Mechanisms of resistance to infection
The primary interest of our laboratory is studying mechanisms of resistance to bacterial infection. Under this broad heading major projects include: 1) Host, bacterial and environmental factors that influence the pathogenesis of gastrointestinal listeriosis and salmonellosis; 2) Immunotoxicology – adverse effects of polycyclic aromatic hydrocarbons on bone marrow cells and hematopoiesis; 3) Bovine respiratory disease - focus on the effects of Mannheimia haemolytica and its leukotoxin on the activities of bovine leukocytes and lung cells; 4) Histophilus somni – adverse effects on bovine endothelial cells as it relates to vasculitis.